🛡️ Signal Detector

Identifies pharmacovigilance signals from safety databases and spontaneous reports using validated statistical detection methods — the core detection engine behind SafeWatch, SignalIQ, and SurveillanceIQ.

Agent-Bound Tool — Not available for direct subscription. Included automatically when you subscribe to: SafeWatch · SignalIQ · SurveillanceIQ

Agent-bound tools work inside agent workflows — you never need to configure or call them separately. View all tools →

Tool Details

TypeAgent-Bound

Used bySafeWatch · SignalIQ · SurveillanceIQ

Data isolation✓ 6 layers

Audit trail✓ Immutable

This tool works inside agent workflows automatically. It is included in every result produced by the agents that use it.

Features

What Signal Detector does.

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Proportional Reporting Ratio analysis

Calculates proportional reporting ratios across your safety database — identifying adverse events reported disproportionately frequently for your product compared to the background reporting rate.

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Bayesian confidence propagation

Bayesian signal detection methods provide confidence estimates for each detected signal — distinguishing strong signals from noise in databases with varying event frequencies.

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Literature signal integration

Published literature is monitored alongside spontaneous reports — ensuring signals emerging in academic publications are integrated with your own safety data.

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Continuous background monitoring

Signal detection runs continuously against your safety database — identifying new signals as soon as sufficient data exists to meet detection thresholds.

Advantages

Why it matters.

Signals no individual could see become visible

Statistical methods identify patterns in large datasets that no individual reviewer could identify by reading reports one at a time.

Literature monitoring integrated with safety data

Signal Detector integrates both spontaneous reports and literature signals — giving your safety team a complete picture from all available sources.

Detection thresholds maintained consistently

Signal Detector applies the same detection thresholds consistently — regardless of workload or reviewer experience.

WHO-UMC and ICH E2C compliant

Signal detection methods align with WHO-UMC recommendations and ICH E2C periodic benefit-risk evaluation guidelines.